Background gamma rhythmicity and attention in cortical local circuits: a computational study.

  title={Background gamma rhythmicity and attention in cortical local circuits: a computational study.},
  author={Christoph B{\"o}rgers and Steven Epstein and Nancy J. Kopell},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102 19},
  • C. Börgers, S. Epstein, N. Kopell
  • Published 10 May 2005
  • Biology, Psychology
  • Proceedings of the National Academy of Sciences of the United States of America
We describe a simple computational model, based on generic features of cortical local circuits, that links cholinergic neuromodulation, gamma rhythmicity, and attentional selection. We propose that cholinergic modulation, by reducing adaptation currents in principal cells, induces a transition from asynchronous spontaneous activity to a "background" gamma rhythm (resembling the persistent gamma rhythms evoked in vitro by cholinergic agonists) in which individual principal cells participate… 

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