Bacillus subtilis guanine deaminase is encoded by the yknA gene and is induced during growth with purines as the nitrogen source.

@article{Nygaard2000BacillusSG,
  title={Bacillus subtilis guanine deaminase is encoded by the yknA gene and is induced during growth with purines as the nitrogen source.},
  author={Per Holm Nygaard and Soren M{\"u}ller Bested and Karen Andersen and Hans Henrik Saxild},
  journal={Microbiology},
  year={2000},
  volume={146 Pt 12},
  pages={3061-9}
}
Bacillus subtilis can utilize the purine bases adenine, hypoxanthine and xanthine as nitrogen sources. The utilization of guanine as a nitrogen source is reported here. The first step is the deamination of guanine to xanthine catalysed by guanine deaminase (GDEase). To isolate mutants defective in GDEase activity, a collection of mutant strains was screened for strains unable to use guanine as a nitrogen source. The strain BFA1819 (yknA) showed the expected phenotype and no GDEase activity… CONTINUE READING