Bacillus subtilis RecN binds and protects 3′-single-stranded DNA extensions in the presence of ATP

Abstract

Bacillus subtilis RecN appears to be an early detector of breaks in double-stranded DNA. In vivo, RecN forms discrete nucleoid-associated structures and in vitro exhibits Mg2+-dependent single-stranded (ss) DNA binding and ssDNA-dependent ATPase activities. In the presence of ATP or ADP, RecN assembles to form large networks with ssDNA molecules (designated… (More)

Topics

6 Figures and Tables

Slides referencing similar topics