Bacillus subtilis: A Model System for Heterologous Gene Expression

  title={Bacillus subtilis: A Model System for Heterologous Gene Expression},
  author={Roy H. Doi and Xiao-song He and P. M. McCready and Nouna Bakheit},
Bacillus subtilis has several features that make it a favorable system for studying the expression of foreign genes. B. subtilis is a non-pathogenic organism and makes no known endotoxins and therefore poses no health threat. Furthermore, it has been used historically for making food products in the Orient and has been used widely in industry to produce enzymes such as proteases, alpha-amylases and other degradative enzymes in large quantities. The cells grow readily to high densities in… CONTINUE READING