Bacillus sphaericus mosquitocidal toxin (MTX) and pierisin: the enigmatic offspring from the family of ADP‐ribosyltransferases

@article{Carpusca2006BacillusSM,
  title={Bacillus sphaericus mosquitocidal toxin (MTX) and pierisin: the enigmatic offspring from the family of ADP‐ribosyltransferases},
  author={Irina Carpusca and T. Jank and K. Aktories},
  journal={Molecular Microbiology},
  year={2006},
  volume={62}
}
The mosquitocidal toxin (MTX) from Bacillus sphaericus and the apoptosis‐inducing pierisin‐1 from the cabbage butterfly Pieris rapae are two of the most intriguing members of the family of ADP‐ribosyltransferases. They are both ∼100 kDa proteins, composed of an N‐terminal ADP‐ribosyltransferase (∼27 kDa) and a C‐terminal putative binding and translocation domain (∼70 kDa) consisting of four ricin‐B‐like domains. While they both share structural homologies, with an overall amino acid sequence… Expand
Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.
Structural basis of autoinhibition and activation of the DNA-targeting ADP-ribosyltransferase pierisin-1
Structure and mode of action of a mosquitocidal holotoxin.
Mtx Toxins Synergize Bacillus sphaericus and Cry11Aa against Susceptible and Insecticide-Resistant Culex quinquefasciatus Larvae
The natural history of ADP-ribosyltransferases and the ADP-ribosylation system.
...
1
2
3
4
...

References

SHOWING 1-10 OF 45 REFERENCES
The ADP-ribosylating Mosquitocidal Toxin from Bacillus sphaericus
Structure of the mosquitocidal toxin from Bacillus sphaericus.
Distinct roles for the N- and C-terminal regions in the cytotoxicity of pierisin-1, a putative ADP-ribosylating toxin from cabbage butterfly, against mammalian cells
Analysis of HPRT and supF mutations caused by pierisin-1, a guanine specific ADP-ribosylating toxin derived from the cabbage butterfly.
Proteolytic processing of the mosquitocidal toxin from Bacillus sphaericus SSII-1.
Purification and cloning of pierisin-2, an apoptosis-inducing protein from the cabbage butterfly, Pieris brassicae.
...
1
2
3
4
5
...