Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth

@article{Gabrielli2009BacillusCA,
  title={Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth},
  author={Maurizio Gabrielli and Ernesto Cristiano Lauritano and Emidio Scarpellini and Andrea Lupascu and Veronica Ojetti and Giovanni Battista Gasbarrini and Nicol{\'o} Gentiloni Silveri and Antonio Gasbarrini},
  journal={The American Journal of Gastroenterology},
  year={2009},
  volume={104},
  pages={1327-1328}
}
Key Methodlated by the chi-squared test, and associations were estimated by the OR with 95 % CI. Statistical analyses used Epidat version 3.1. We found no evidence of associations between idiopathic achalasia and the NOS2A rs1060826 single nucleotide polymorphism (TT vs. carriers of allele G: OR = 0.88, 95 % CI 0.60 – 1.29, P = 0.52) ( Table 1 ). We observed, similar to the earlier study, a lower frequency of the genotype AA in achalasia than in controls (18 vs. 20 % ); however, in a pooled analysis…

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The results confirm the association between achalasia and HLA-DQ1 allele and suggest that TNFa11 is a marker for a protective allele for the disease, present on the B7-DRB1*1501 (7.1) ancestral haplotype in this population.

Small Intestinal Bacterial Overgrowth: Diagnosis and Treatment

Breath tests (glucose and/or lactulose breath tests) have been proposed as a sensitive and simple tool for the diagnosis of bacterial overgrowth, being non-invasive and inexpensive compared to the gold standard represented by the culture of intestinal aspirates.

Association Between Achalasia and Nitric Oxide Synthase Gene Polymorphisms

Data suggest that NOS gene polymorphisms are not involved in the susceptibility to and nature of the clinical course of sporadic achalasia, and studies in a greater number of patients are required to analyze the tendency toward a higher prevalence of genotypes iNOS22*A/A and eNOS*4a4a.

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