Bacillus anthracis spores of the bclA mutant exhibit increased adherence to epithelial cells, fibroblasts, and endothelial cells but not to macrophages.

@article{Bozue2007BacillusAS,
  title={Bacillus anthracis spores of the bclA mutant exhibit increased adherence to epithelial cells, fibroblasts, and endothelial cells but not to macrophages.},
  author={Joel A Bozue and Krishna L. Moody and Christopher K. Cote and Bradley G. Stiles and Arthur M. Friedlander and Susan L. Welkos and Martha L Hale},
  journal={Infection and immunity},
  year={2007},
  volume={75 9},
  pages={4498-505}
}
Bacillus anthracis is the causative agent of anthrax, and the spore form of the bacterium represents the infectious particle introduced into a host. The spore is surrounded by an exosporium, a loose-fitting membrane composed of proteins and carbohydrates from which hair-like projections extend. These projections are composed mainly of BclA (Bacillus-collagen-like protein of B. anthracis). To date, exact roles of the exosporium structure and BclA protein remain undetermined. We examined… CONTINUE READING

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