Bacillus Calmette-Guerin alleviates airway inflammation and remodeling by preventing TGF-β1 induced epithelial-mesenchymal transition.

@article{Tian2017BacillusCA,
  title={Bacillus Calmette-Guerin alleviates airway inflammation and remodeling by preventing TGF-β1 induced epithelial-mesenchymal transition.},
  author={Xinrui Tian and Xinli Tian and Rujie Huo and Qin Chang and Guoping Zheng and Yan Du and Yan Chen and B. F. Niu},
  journal={Human vaccines & immunotherapeutics},
  year={2017},
  volume={13 8},
  pages={
          1758-1764
        }
}
Bacillus Calmette-Guerin (BCG) is a potent agent for the prevention of tuberculosis. Current studies have regarded BCG as an immunomodulator. However, there is little information on whether it can be used to inhibit airway inflammation and airway remodeling caused by asthma. Therefore, in this study, we investigate the role of epithelial-mesenchymal… CONTINUE READING