Bacille Calmette-Guérin vaccine-induced disease in HIV-infected and HIV-uninfected children.

  title={Bacille Calmette-Gu{\'e}rin vaccine-induced disease in HIV-infected and HIV-uninfected children.},
  author={Anneke Catharina Hesseling and Helena Rabie and Ben J. Marais and Marleen Manders and Michal Lip{\vs} and Hendrik Simon Schaaf and Robert Gie and M F Cotton and Paul D van Helden and Robin Mark Warren and Nulda Beyers},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={42 4},
BACKGROUND Bacille Calmette-Guérin (BCG)--a live, attenuated vaccine--is routinely given to neonates in settings where tuberculosis is endemic, irrespective of human immunodeficiency virus (HIV) exposure. HIV-infected infants and other immunodeficient infants are at risk of BCG-related complications. We report the presentation, treatment, and mortality of children who develop BCG disease, with emphasis on HIV-infected children. In addition, we present a revised classification of BCG disease in… CONTINUE READING
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