Baboon and cotton-top tamarin B2m cDNA sequences and the evolution of primate beta 2-microglobulin.

@article{Ruiz1994BaboonAC,
  title={Baboon and cotton-top tamarin B2m cDNA sequences and the evolution of primate beta 2-microglobulin.},
  author={Robert E. Ruiz and Bruce Lee Hall and Carolyn Doyle and Frances E. Ward},
  journal={Human immunology},
  year={1994},
  volume={39 3},
  pages={188-94}
}
Nonhuman primates represent phylogenetic intermediates for studying the divergence of human and murine beta 2Ms. We report the nucleotide sequences of B2m cDNA clones from a baboon cell line, 26CB-1 (Papio hamadryas; primates: Cercopithecoidea), and a cotton-top tamarin cell line, 1605L (Saguinus oedipus; primates: Ceboidea). The baboon and tamarin B2m sequences indicate a very slow rate of B2m evolution in primates relative to that in murid rodents. Phenotypic evolution of beta 2M has also… CONTINUE READING