Baboon/dSmad2 TGF-beta signaling is required during late larval stage for development of adult-specific neurons.

@article{Zheng2006BaboondSmad2TS,
  title={Baboon/dSmad2 TGF-beta signaling is required during late larval stage for development of adult-specific neurons.},
  author={Xiaoyan Zheng and Christopher T. Zugates and Zouyan Lu and Lei Shi and Jia-min Bai and Tzumin Lee},
  journal={The EMBO journal},
  year={2006},
  volume={25 3},
  pages={615-27}
}
The intermingling of larval functional neurons with adult-specific neurons during metamorphosis contributes to the development of the adult Drosophila brain. To better understand this process, we characterized the development of a dorsal cluster (DC) of Atonal-positive neurons that are born at early larval stages but do not undergo extensive morphogenesis until pupal formation. We found that Baboon(Babo)/dSmad2-mediated TGF-beta signaling, known to be essential for remodeling of larval… CONTINUE READING

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