BUdR-Giemsa labeling and satellite association in human leukocytes

  title={BUdR-Giemsa labeling and satellite association in human leukocytes},
  author={Bernd Beek},
  journal={Human Genetics},
Satellite associations were analysed in differentially stained human leukocyte chromosomes, obtained from four patients with Down's syndrome and four normal probands. A particular type of close association between two acrocentrics, showing a non-random arrangement of sister chromatids in a concordant dark-to-dark and light-to-light alignment, was found to be more common in patients with Down's syndrome compared with the normal controls. Apart from this particular type of association, sister… CONTINUE READING

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