BUDR inhibition of post-DMSO-induced erythroleukaemia cell differentiation in vitro.

THE ADDITION of dimethylsulfoxide (DMSO) to suspension cultures of Friend leukaemia cells results in the erythroid differentiation of a substantial proportion of cells in the culture (Friend et al., 1971). The continuous presence of DMSO in the culture medium is not necessary for differentiation to occur since exposure of the cells to DMSO for 2 days… CONTINUE READING