BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1

@inproceedings{Liu2015BTG1PA,
  title={BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1},
  author={Chunhui Liu and Tao Tao and Bin Xu and Kai Lu and Lei Zhang and Liang Jiang and Shuqiu Chen and Dachuang Liu and Xiaowen Zhang and N Cao and Ming Chen},
  booktitle={Oncology letters},
  year={2015}
}
B-cell translocation gene 1 (BTG1) is a member of the BTG/transducer of Erb family. BTG1 regulates cell cycle progression, inhibits proliferation, promotes apoptosis and stimulates cellular differentiation in multiple cell types. However, the functions of BTG1 in renal cell carcinoma (RCC) remain unclear. Therefore, the present study investigated the role of BTG1 in RCC tissue samples and 786-O RCC cells. RCC tissues and cells exhibited significantly weaker BTG1 protein and mRNA expression… CONTINUE READING
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