BTB/POZ domain-containing protein 7: epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma.

@article{Tao2013BTBPOZDP,
  title={BTB/POZ domain-containing protein 7: epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma.},
  author={Yi-ming Tao and Jin-lin Huang and Shan Zeng and Sai Zhang and Xue-gong Fan and Zhiming Wang and Hui-xiang Yang and Xiaoyan Yuan and Pu Patrick Wang and Fan Wu and Jia Luo and De-Yu Zeng and Hong Shen},
  journal={Hepatology},
  year={2013},
  volume={57 6},
  pages={2326-37}
}
UNLABELLED Epithelial-mesenchymal transition (EMT) is a critical step in the metastasis of hepatocellular carcinoma (HCC). BTB/POZ domain-containing protein 7 (BTBD7) regulates EMT-associated proteins implicated in HCC progression. However, the role(s) of BTBD7 in HCC have not been identified. Using highly metastatic HCC HCCLM3 cells, immortalized L02 hepatocytes, metastatic HCC animal models, and three independent cohorts of HCC patient specimens, we aimed to determine the involvement of BTBD7… CONTINUE READING

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