BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake.

@article{Baier2011BSAAO,
  title={BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake.},
  author={Grit Baier and Cristiane Rocha da Costa and Anke Zeller and Daniela Baumann and Cl{\'a}udia Sayer and P. H. H. Ara{\'u}jo and Volker Mailaender and Anna Musyanovych and Katharina Landfester},
  journal={Macromolecular bioscience},
  year={2011},
  volume={11 5},
  pages={628-38}
}
BSA adsorption onto negatively and positively charged polystyrene nanoparticles was investigated. The nanoparticles were characterized in terms of particle size, zeta potential, surface group density, and morphology. The adsorption behavior of BSA on the particle surface, as a function of pH and overall charge of the particle, was studied using ITC. Different thermodynamic data such as enthalpy changes upon binding and stoichiometry of the systems were determined and discussed. The degree of… CONTINUE READING
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All about Albumin – Biochemistry, Genetics, and Medical Applications

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