BRI1 is a critical component of a plasma-membrane receptor for plant steroids

@article{Wang2001BRI1IA,
  title={BRI1 is a critical component of a plasma-membrane receptor for plant steroids},
  author={Zhi-Yong Wang and H. Seto and S. Fujioka and S. Yoshida and J. Chory},
  journal={Nature},
  year={2001},
  volume={410},
  pages={380-383}
}
Most multicellular organisms use steroids as signalling molecules for physiological and developmental regulation. Two different modes of steroid action have been described in animal systems: the well-studied gene regulation response mediated by nuclear receptors, and the rapid non-genomic responses mediated by proposed membrane-bound receptors. Plant genomes do not seem to encode members of the nuclear receptor superfamily. However, a transmembrane receptor kinase, brassinosteroid-insensitive1… Expand
Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1
TLDR
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Crystal structures reveal why the brassinosteroid receptor kinase requires another kinase helper protein for activation and reveal how known missense mutations in BRI1 and in SERKs modulate brass inosteroid signaling and the targeting mechanism of B RI1 receptor antagonists. Expand
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Ligand perception, activation, and early signaling of plant steroid receptor brassinosteroid insensitive 1.
TLDR
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TLDR
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Regulation of Three Key Kinases of Brassinosteroid Signaling Pathway
TLDR
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Two possible explanations of the rapid responses to steroid hormones in animal cells still remains obscure are shown and results of experiments performed with ovarian hormones, that led their authors to the hypothesis explaining rapid steroid actions without distinct membrane steroid receptors are reviewed. Expand
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