BREAKDOWN OF HIGH ENERGY PHOSPHATE COMPOUNDS IN BRAIN SLICES IN RELATION WITH AN INCREASE IN PERMEABILITY TO CATIONS.

@article{Yoshida1963BREAKDOWNOH,
  title={BREAKDOWN OF HIGH ENERGY PHOSPHATE COMPOUNDS IN BRAIN SLICES IN RELATION WITH AN INCREASE IN PERMEABILITY TO CATIONS.},
  author={H. Yoshida and H. Fujisawa and K. Kajikawa},
  journal={Japanese journal of pharmacology},
  year={1963},
  volume={13},
  pages={
          297-304
        }
}
It was shown in our previous paper (1) that protoveratrine and EDTA caused a remarkable increase in passive permeability of the membrane of brain slices to cations and this increase was completely prevented by so-called stabilizers such as cocaine and calcium ion. Protoveratrine and EDTA are known to be depolarizers (2) and the effects of these drugs on brain slices were considered to represent a model of natural excitation of the nerve cell membrane. An increase in respiration of brain slices… Expand