BRCA1 pathway function in basal-like breast cancer cells.

@article{Hill2014BRCA1PF,
  title={BRCA1 pathway function in basal-like breast cancer cells.},
  author={Sarah J. Hill and Allison P. Clark and Daniel P. Silver and David M. Livingston},
  journal={Molecular and cellular biology},
  year={2014},
  volume={34 20},
  pages={3828-42}
}
Sporadic basal-like cancers (BLCs) are a common subtype of breast cancer that share multiple biological properties with BRCA1-mutated breast tumors. Despite being BRCA1(+/+), sporadic BLCs are widely viewed as phenocopies of BRCA1-mutated breast cancers, because they are hypothesized to manifest a BRCA1 functional defect or breakdown of a pathway(s) in which BRCA1 plays a major role. The role of BRCA1 in the repair of double-strand DNA breaks by homologous recombination (HR) is its best… CONTINUE READING
Highly Cited
This paper has 29 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…