BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

@article{Tassone2003BRCA1EM,
  title={BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells},
  author={Pierfrancesco Tassone and Pierosandro Tagliaferri and Anita Perricelli and Simona Blotta and Barbara Quaresima and Maria Luisa Martelli and Ajay Goel and Verena Barbieri and F. S. Costanzo and Clement Richard Boland and Salvatore Venuta},
  journal={British Journal of Cancer},
  year={2003},
  volume={88},
  pages={1285 - 1291}
}
Germline mutations of the tumour suppressor gene BRCA1 are involved in the predisposition and development of breast cancer and account for 20–45% of all hereditary cases. There is an increasing evidence that these tumours are characterised by a specific phenotype and pattern of gene expression. We have hypothesised that differences in chemosensitivity might… CONTINUE READING