BRAF vs RAS oncogenes: are mutations of the same pathway equal? differential signalling and therapeutic implications

Abstract

As the increased knowledge of tumour heterogeneity and genetic alterations progresses, it exemplifies the need for further personalized medicine in modern cancer management. Here, the similarities but also the differential effects of RAS and BRAF oncogenic signalling are examined and further implications in personalized cancer diagnosis and therapy are… (More)

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