BRAF mutations in melanocytic tumors (nevi and melanomas) from organ transplant recipients.

@article{Kanitakis2010BRAFMI,
  title={BRAF mutations in melanocytic tumors (nevi and melanomas) from organ transplant recipients.},
  author={Jean Kanitakis and Sylvie Baldassini and Viviana Lora and Sylvie Euvrard},
  journal={European journal of dermatology : EJD},
  year={2010},
  volume={20 2},
  pages={167-71}
}
BRAF is a gene of the RAF family of kinases, frequently mutated in benign and malignant melanocytic tumors (nevi and melanomas). Organ transplant recipients are at high risk for developing various tumors, including melanocytic ones. We studied a group of 129 melanocytic tumors including various subtypes of nevi (n: 114) and melanomas (n: 15) excised from transplant (n: 63) and control (non-immunosuppressed) patients (n: 66) as to BRAF mutation status. Mutation research was performed after… CONTINUE READING