BRAF mutation analysis of fine-needle aspiration biopsies of papillary thyroid carcinoma: impact on diagnosis and prognosis.

  title={BRAF mutation analysis of fine-needle aspiration biopsies of papillary thyroid carcinoma: impact on diagnosis and prognosis.},
  author={Agnes Basas Colanta and Oscar Lin and Laura J. Tafe and Ronald A. Ghossein and Kh{\'e}doudja Nafa and Talia Mitchell and Marc Ladanyi and Maria E. Arcila},
  journal={Acta cytologica},
  volume={55 6},
OBJECTIVE The BRAF V600E mutation has been associated with aggressive disease in papillary thyroid carcinoma (PTC). Molecular testing has been proposed as a useful adjunct to cytology in the diagnosis of malignancy and for tailoring clinical management. The aims of our study were to evaluate the BRAF mutational status using archived fine-needle aspiration biopsy (FNAB) material from patients with long-term follow-up and to correlate it with the original cytology diagnosis, clinicopathological… CONTINUE READING
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