BRAF V600E mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas.

@article{Lee2015BRAFVM,
  title={BRAF V600E mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas.},
  author={Dakeun Lee and Young Hye Cho and So Young Kang and Nara Yoon and Chang Ohk Sung and Yeon-lim Suh},
  journal={Journal of surgical oncology},
  year={2015},
  volume={111 3},
  pages={
          359-64
        }
}
BACKGROUND BRAF mutation has received a great deal of attention in neuro-oncology field, recently. This study aimed to investigate the incidence and the clinical significance of BRAF(V600E) in low-grade glial tumors. METHODS An institutional cohort of 105 brain tumors (51 dysembryoplastic neuroepithelial tumors (DNTs), 14 subependymal giant cell astrocytomas (SEGAs), 12 glioblastoma with neuronal marker expression (GBM-N), and 28 pleomorphic xanthoastrocytomas (PXAs)) from 100 patients were… CONTINUE READING
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