BRAF Inhibitor-Induced Antitumoral Granulomatous Dermatitis Eruption in Advanced Melanoma.

@article{Garrido2015BRAFIA,
  title={BRAF Inhibitor-Induced Antitumoral Granulomatous Dermatitis Eruption in Advanced Melanoma.},
  author={M Concepci{\'o}n Dom{\'i}nguez Garrido and Carlota Gutierrez and Erica Riveiro-Falkenbach and Pablo Luis Ortiz and Jos{\'e} Luis Rodr{\'i}guez-Peralto},
  journal={The American Journal of dermatopathology},
  year={2015},
  volume={37 10},
  pages={795-8}
}
Recent advances in targeting BRAF mutations, which occur in roughly 50% of the melanomas, have improved response rates and overall survival in patients with advanced disease. With the increasingly extensive use of the drug, new, nonpreventable, cutaneous and noncutaneous toxicities keep arising as infrequent adverse effects. We report a 55-year-old man with a history of metastatic melanoma treated with the dabrafenib who presented, 10 months after the initiation of the treatment, with… CONTINUE READING

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