BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease.

@article{Shum2013BPIFB1IA,
  title={BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease.},
  author={Anthony K. Shum and Mohammad Alimohammadi and Catherine L Tan and Mickie H Cheng and Todd C. Metzger and Christopher S. Law and Wint Wah Lwin and Jaakko Perheentupa and H{\'e}l{\`e}ne Bour-Jordan and Jean Claude Carel and Eystein Sverre Husebye and Filippo de Luca and Christer Janson and Ravishankar B Sargur and No{\'e}mie Dubois and Merja Kajosaari and Paul J Wolters and Harold A Chapman and Olle K{\"a}mpe and Mark S. Anderson},
  journal={Science translational medicine},
  year={2013},
  volume={5 206},
  pages={206ra139}
}
Interstitial lung disease (ILD) is a complex and heterogeneous disorder that is often associated with autoimmune syndromes. Despite the connection between ILD and autoimmunity, it remains unclear whether ILD can develop from an autoimmune response that specifically targets the lung parenchyma. We examined a severe form of autoimmune disease, autoimmune polyglandular syndrome type 1 (APS1), and established a strong link between an autoimmune response to the lung-specific protein BPIFB1… CONTINUE READING
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