BOLD response during uncoupling of neuronal activity and CBF

  title={BOLD response during uncoupling of neuronal activity and CBF},
  author={M. Burke and Ch. Ph. B{\"u}hrle},
The widely used technique of functional magnetic resonance imaging (fMRI) based on the blood oxygenation level-dependent (BOLD) effect is a tool for the investigation of changes in local brain activity upon stimulation. The principle of measurement is based on the assumption that there is a strong coupling between changes in neural activity, metabolism, vascular response and oxygen extraction in the area under investigation. As fMRI is on the way to become a routine tool in clinical… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 20 extracted citations

Pharmacological uncoupling of activation induced increases in CBF and CMRO2.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2010
View 6 Excerpts
Highly Influenced

Recent advances in research on nitrergic nerve-mediated vasodilatation

Pflügers Archiv - European Journal of Physiology • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…