BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells.

@article{Tsuchiya2016BODIPYlabeledFA,
  title={BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells.},
  author={Akira Tsuchiya and Siti Norhajah Hashim and Shoko Ise and Takafumi Furuhata and Kiyohiko Kawai and Rie Wakabayashi and Masahiro Goto and Noriho Kamiya and Shinsuke Sando},
  journal={Analytical sciences : the international journal of the Japan Society for Analytical Chemistry},
  year={2016},
  volume={32 5},
  pages={
          543-7
        }
}
An on-cell aptamer sensor has the potential to reveal cell-cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-γ and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.