BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.

  title={BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.},
  author={Patrick Tang and Mohammad Rubayet Hasan and Hiam Chemaitelly and Hadi Mohamad Yassine and Fatiha M. Benslimane and Hebah A. Al Khatib and Sawsan AlMukdad and Peter Coyle and Houssein H. Ayoub and Zaina Al Kanaani and Einas Al Kuwari and Andrew Jeremijenko and Anvar Hassan Kaleeckal and Ali Nizar Latif and Riyazuddin Mohammad Shaik and Hanan F. Abdul Rahim and Gheyath K. Nasrallah and Mohamed Ghaith Al Kuwari and Hamad Eid Al Romaihi and Adeel Ajwad Butt and Mohamed H. Al-Thani and Abdullatif Al Khal and Roberto Bertollini and Laith Jamal Abu-Raddad},
  journal={Nature medicine},
With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines against infection with Delta in Qatar's population. BNT162b2 effectiveness against any, symptomatic or asymptomatic, Delta infection was 45.3% (95% CI, 22.0-61.6%) ≥14 d after the first vaccine dose, but only 51.9% (95% CI, 47.0-56.4%) ≥14 d after the second dose, with 50% of… 

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