BMP4 supports noradrenergic differentiation by a PKA-dependent mechanism.

@article{Liu2005BMP4SN,
  title={BMP4 supports noradrenergic differentiation by a PKA-dependent mechanism.},
  author={Hongbin Liu and Joseph F Margiotta and Marthe J. Howard},
  journal={Developmental biology},
  year={2005},
  volume={286 2},
  pages={
          521-36
        }
}
Differentiation of neural crest-derived noradrenergic neurons depends upon signaling mediated downstream of BMP binding to cognate receptors and involving cAMP. Compiled data from many groups suggest that neurogenesis and cell type-specific noradrenergic marker gene regulation is coordinated through the expression and function of the basic helix-loop-helix DNA binding protein HAND2 and the homeodomain DNA binding protein Phox2a. However, information detailing how BMP-mediated signaling and… CONTINUE READING
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Evidence for an important role of HAND genes in the network of transcriptional regulators controlling sympathetic neuron development

  • M. J. Howard, M. Stanke, C. Schneider, X. Wu, H. Rohrer
  • Development
  • 2000
Highly Influential
30 Excerpts

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