BMP-signaling regulates the generation of hair-cells.

  title={BMP-signaling regulates the generation of hair-cells.},
  author={Cristina Pujades and Andr{\'e}s Kamaid and Berta Alsina and Fernando Gir{\'a}ldez},
  journal={Developmental biology},
  volume={292 1},
Bone morphogenetic proteins (BMPs) are diffusible molecules involved in a variety of cellular interactions during development. Bmp4 expression accompanies the development of the ear sensory organs during patterning and specification of sensory cell fates, yet there is no understanding of the role of BMP4 in this process. The present work was aimed at exploring the effects of BMP-signaling on the development of hair-cells. For this purpose, we studied gene expression, cell proliferation and cell… CONTINUE READING


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