BMP signaling in rats with TNBS-induced colitis following BMP7 therapy.
@article{Mari2012BMPSI, title={BMP signaling in rats with TNBS-induced colitis following BMP7 therapy.}, author={Ivana Mari{\'c} and Natalia Ku{\vc}i{\'c} and Tamara Turk Wensveen and Ivana Smoljan and Blaženka Grahovac and Sanja Zori{\vc}i{\'c} Cvek and Tanja Celic and Dragica Bobinac and Slobodan Vukicevic}, journal={American journal of physiology. Gastrointestinal and liver physiology}, year={2012}, volume={302 10}, pages={ G1151-62 } }
Beyond stimulating bone formation, bone morphogenetic proteins (BMPs) are important in development, inflammation, and malignancy of the gut. We have previously shown that BMP7 has a regenerative, anti-inflammatory, and antiproliferative effect on experimental inflammatory bowel disease (IBD) in rats. To further investigate the BMP signaling pathway we monitored the effect of BMP7 therapy on the BMP signaling components in the rat colon during different stages of experimentally induced colitis…
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