BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways.

@article{Cook2014BMPSB,
  title={BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways.},
  author={Brandoch D. Cook and Todd Evans},
  journal={Blood},
  year={2014},
  volume={124 3},
  pages={
          393-402
        }
}
Bone morphogenetic protein (BMP) signaling regulates early hematopoietic development, proceeding from mesoderm patterning through the progressive commitment and differentiation of progenitor cells. The BMP pathway signals largely through receptor-mediated activation of Mothers Against Decapentaplegic homolog (SMAD) proteins, although alternate pathways are modulated through various components of mitogen-activated protein kinase (MAPK) signaling. Using a conditional, short hairpin RNA (shRNA… Expand
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