BMP and activin receptor expression in lens development.

  title={BMP and activin receptor expression in lens development.},
  author={Robbert U. de Iongh and Yongjuan Chen and Maria Irene Kokkinos and John W. McAvoy},
  journal={Molecular vision},
PURPOSE Members of the TGFbeta super-family have been shown to play important roles in lens development, including lens placode formation and fiber differentiation, and also induce changes characteristic of some forms of cataract. Previous studies demonstrated expression of TGFbeta receptors during lens morphogenesis. However, the expression patterns of activin and BMP receptors or their signaling mediators, the Smad proteins, have not been well documented. In this study we examine the spatio… CONTINUE READING
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