BMP-2 release and dose-response studies in hydroxyapatite and beta-tricalcium phosphate.

@article{Tazaki2009BMP2RA,
  title={BMP-2 release and dose-response studies in hydroxyapatite and beta-tricalcium phosphate.},
  author={Junichi Tazaki and Masaru Murata and Toshiyuki Akazawa and Masaya Yamamoto and Katsutoshi Ito and Makoto Arisue and Takanori Shibata and Yasuhiko Tabata},
  journal={Bio-medical materials and engineering},
  year={2009},
  volume={19 2-3},
  pages={141-6}
}
The purpose of this study is to compare in vivo retention of BMP-2 and bone induction in HAp (porosity: 60-80%, pore size: 100-600 mum, sintering temperature: 800 degrees C, surface area: 1 m(2)/g) and beta-TCP (porosity: 75%, pore size: 100-400 mum, sintering temperature: 1050 degrees C, surface area: 4 m(2)/g). We estimated the in vivo release profile of (125)I-labeled BMP-2 and bone induction of hard tissues histologically. The amount of BMP-2 remaining in the beta-TCP at 1 day after… CONTINUE READING