BMD Regulation on Mouse Distal Chromosome 1, Candidate Genes, and Response to Ovariectomy or Dietary Fat

@inproceedings{Beamer2011BMDRO,
  title={BMD Regulation on Mouse Distal Chromosome 1, Candidate Genes, and Response to Ovariectomy or Dietary Fat},
  author={Wesley G. Beamer and Kathryn L. Shultz and Harold F Coombs and Victoria Demambro and Laura G Reinholdt and Cheryl L. Ackert-Bicknell and Ernesto Canalis and Clifford J. Rosen and Leah Rae B Donahue},
  booktitle={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2011}
}
The distal end of mouse chromosome 1 (Chr 1) harbors quantitative trait loci (QTLs) that regulate bone mineral density (BMD) and share conserved synteny with human chromosome 1q. The objective of this article was to map this mouse distal Chr 1 region and identify gene(s) responsible for BMD regulation in females. We used X-ray densitometry [ie, dual-energy X-ray Absorptiometry (DXA), micro-computed tomography (µCT), and peripheral quantitative computed tomography (pQCT)] to phenotype a set of… CONTINUE READING