BLAST+: architecture and applications

  title={BLAST+: architecture and applications},
  author={Christiam Camacho and George Coulouris and Vahram Avagyan and Ning Ma and Jason S. Papadopoulos and Kevin Bealer and Thomas L. Madden},
  booktitle={BMC Bioinformatics},
Sequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its use of heuristics, the speed of the current BLAST software is suboptimal for very long queries or database sequences. There are also some shortcomings in the user-interface of the current command-line applications. We describe features and improvements of rewritten BLAST software and introduce new command-line applications. Long query… CONTINUE READING