BK virus

  title={BK virus},
  journal={American Journal of Transplantation},
  • Published 1 October 2004
  • Medicine
  • American Journal of Transplantation
Infection with BK virus (BKV), a polyoma virus, occurs worldwide with seroprevalence rates as high as 60–80% reported among adults in the USA and Europe (1–3). Seroprevalence studies show the peak incidence of primary infection to occur in children 2–5, years of age (4). BKV antibody may be detected in as many as 50% of children by 3 years of age and in nearly 100% of children by 9–10 years of age (1–3). Clinical disease in immunocompetent hosts is rare although cystitis can occur. 


High prevalence of antibodies to BK virus, an SV40-related papovavirus, in residents of Maryland.
Examination of sera for antibodies by indirect fluorescent antibody tests and by conventional and immunofluorescence neutralization tests supported the results of HAI tests, and infection with BK virus appears to be common in early childhood. Expand
BK virus infection in renal transplant recipients
The current understanding of BKV infections among renal transplant patients is reviewed and BK virus is increasingly being recognized as an important pathogen among renal transplants recipients. Expand
Prevalence in England of Antibody to Human Polyomavirus (B.K.)
Tests showed that antibody to this virus was very common in the population and began to be acquired after the age of 1 year, and no clinical illness has so far been associated with the development of this antibody in a series of paired sera from children. Expand
A serological investigation of BK virus and JC virus infections in recipients of renal allografts.
BKV and JCV infections in renal transplant recipients may be caused either by reactivation of the recipient's latent virus or by virus from the donor kidney, but these infections are not associated with adverse outcome in the recipient in the early post-transplant period. Expand
Human polyomavirus infections with JC virus and BK virus in renal transplant patients.
Polyomavirus replication was associated with an increased frequency of transplant related complications and Antibody increases to BK virus were associated with a rising seurum creatinine and need for transplant biopsy. Expand
Prevalence of anti BK virus antibody in Portugal and Norway.
No significant difference between the prevalence and level of BKV IgG could be found between Portugal and Norway, and when comparing the different counties of Portugal. Expand
Pathogenesis and management of polyomavirus infection in transplant recipients.
Clinical syndromes related to polyomavirus infection are summarized in the present review, and strategies for the management of patients who receive transplants are discussed. Expand
Testing for polyomavirus type BK DNA in plasma to identify renal-allograft recipients with viral nephropathy.
Testing for BK virus DNA in plasma from renal-allograft recipients with use of the polymerase chain reaction is a sensitive and specific method for identifying viral nephropathy. Expand
BK virus in solid organ transplant recipients: an emerging syndrome.
Treatment of immunosuppressed patients with polyomavirus viruria is largely supportive and directed toward minimizing Immunosuppression, and improved diagnostic tools and antiviral therapies are needed. Expand
Human Polyomavirus Infection in Renal Allograft Recipients
Cytological and virological studies on 74 patients with functioning renal allografts were undertaken to detect polyomavirus infection of the renal tract and found that patients who were excreting large amounts of polyomvirus shed numerous inclusion-bearing cells which could be detected by cytology. Expand