BK viremia and polyomavirus nephropathy in 352 kidney transplants; risk factors and potential role of mTOR inhibition

@inproceedings{Jacobi2013BKVA,
  title={BK viremia and polyomavirus nephropathy in 352 kidney transplants; risk factors and potential role of mTOR inhibition},
  author={Johannes Jacobi and Antonina Prignitz and Maike B{\"u}ttner and Klaus Korn and A. Weidemann and Karl Friedrich Hilgers and Katharina M Heller and J. W. ten Velden and Antje Kn{\"o}ll and Bernd Wullich and Christoph May and K. Eckardt and Kerstin Amann},
  booktitle={BMC nephrology},
  year={2013}
}
BACKGROUND Polyomavirus BK nephropathy (PyVAN) remains an important cause of early graft dysfunction and graft loss in kidney transplantation. METHODS In this retrospective, single centre cohort study we studied the incidence and outcome of BK viral infection in 352 patients transplanted in 2008-2011. RESULTS During follow-up viral replication was detected in 48 patients (13.6%); 22 patients (6.2%) had biopsy proven PyVAN.In multivariate logistic regression analyses risk factors for BK… CONTINUE READING
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