• DOI:10.1111/j.1749-6632.1975.tb25349.x
Corpus ID: 45625081

BIOLOGICAL EFFECTS OF THE METABOLITES OF DIMETHYL SULFOXIDE *

@article{Kocsis1975BIOLOGICALEO,
  title={BIOLOGICAL EFFECTS OF THE METABOLITES OF DIMETHYL SULFOXIDE *},
  author={J. Kocsis and S. Harkaway and R. Snyder},
  journal={Annals of the New York Academy of Sciences},
  year={1975},
  volume={243}
}

• J. Kocsis, S. Harkaway, R. Snyder
• Published 1975
• Chemistry, Medicine
• Annals of the New York Academy of Sciences

In summary, the effects of dimethyl sulfoxide (DMSO) and its metabolites, dimethyl sulfone (DMSO2) and dimethyl sulfide (DMS), were studied in five selected systems in rats and mice. DMSO enhanced the taurine excretion and the lethality produced by such aromatic hydrocarbons as benzene and chlorobenzene in rats. In mice, DMSO decreased the toxicity such cholinesterase inhibitors as paraoxon and octamethyl pyrophosphoramide. DMSO also lowered the body temperture of rats and reduced the motor… Expand

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