BIN1 is a novel MYC–interacting protein with features of a tumour suppressor

Abstract

BIN1 is a novel protein that interacts with the functionally critical Myc box regions at the N terminus of the MYC oncoprotein. BIN1 is structurally related to amphiphysin, a breast cancer–associated autoimmune antigen, and RVS167, a negative regulator of the yeast cell cycle, suggesting roles in malignancy and cell cycle control. Consistent with this… (More)
DOI: 10.1038/ng0996-69

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Cite this paper

@article{Sakamuro1996BIN1IA, title={BIN1 is a novel MYC–interacting protein with features of a tumour suppressor}, author={Daitoku Sakamuro and Katharine J. Elliott and Robert J Wechsler-Reya and George C. Prendergast}, journal={Nature Genetics}, year={1996}, volume={14}, pages={69-77} }