BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer.

Abstract

We have recently demonstrated that BEX2 is differentially expressed in primary breast tumors and BEX2 expression is required for the Nerve Growth factor inhibition of ceramide-induced apoptosis in breast cancer. In this study we investigate the functional role of BEX2 in the survival and growth of breast cancer cells. We demonstrate that BEX2 downregulation… (More)
DOI: 10.1002/ijc.24866

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