Corpus ID: 35435119

BENEFICIAL EFFECTS OF SOME VITAMINS AND CALCIUM ON FLUORIDE AND ALUMINIUM TOXICITY ON GASTROCNEMIUS MUSCLE AND LIVER OF MALE MICE

@inproceedings{Chinoy2002BENEFICIALEO,
  title={BENEFICIAL EFFECTS OF SOME VITAMINS AND CALCIUM ON FLUORIDE AND ALUMINIUM TOXICITY ON GASTROCNEMIUS MUSCLE AND LIVER OF MALE MICE},
  author={N. Chinoy and M. Memon},
  year={2002}
}
Treatment of male mice (Mus musculus) with sodium fluoride (NaF, 10 mg/kg body weight), alone or in combination with aluminium chloride (AlCl3, 200 mg/kg body weight), was investigated for its effects on gastrocnemius muscle and liver. Recovery after one-month withdrawal of treatment and responses to some antidotes, viz calcium, ascorbic acid, and vitamin E administered alone or in combination were also studied. NaF alone or in combination with AlCl3 caused a significant decrease in protein… Expand
ARSENIC AND FLUORIDE INDUCED TOXICITY IN GASTROCNEMIUS MUSCLE OF MICE AND ITS REVERSAL BY THERAPEUTIC AGENTS
Sodium fluoride (NaF, 5 mg/kg bw) and arsenic trioxide (As2O3, 0.05 mg/ kg bw), individually or in combination, were administered orally for 30 days to Swiss strain adult female mice (Mus musculus).Expand
BENEFICIAL EFFECTS OF CERTAIN ANTIDOTES IN MITIGATING FLUORIDE AND/OR ARSENIC INDUCED HEPATOTOXICITY IN MICE
SUMMARY: The effects of co-administration for 30 days of sodium fluoride (NaF) (5 mg/kg body weight) and/or arsenic trioxide (As2O3) (0.5 mg/kg body weight) on the liver of female mice (Mus musculus)Expand
CYPERMETHRIN AND SODIUM FLUORIDE SYNERGISTIC EFFECT ON OXIDATIVE ENZYMES IN MUSCLE AND KIDNEY OF ALBINO MICE
Present study was aimed to investigate the synergistic effect of cypermethrin and sodium fluoride on oxidative enzymes. Albino mice were treated orally with cypermethrin and sodium fluorideExpand
PROTECTIVE ACTION OF MELATONIN AGAINST FLUORIDE-INDUCED HEPATOTOXICITY IN ADULT FEMALE MICE
Given peritoneally over a 30-day period, melatonin (10 mg/kg bw/day) effectively countered toxic effects of orally administered sodium fluoride (NaF, 10 mg/kg bw/day) in the liver of adult femaleExpand
Effects of Melatonin and Epiphyseal Proteins on Fluoride-Induced Adverse Changes in Antioxidant Status of Heart, Liver, and Kidney of Rats
TLDR
The present data suggest that F can induce oxidative stress in liver, heart, and kidney of female rats which may be a mechanism in F toxicity and these adverse effects can be ameliorated by buffalo (Bubalus bubalis) epiphyseal proteins and melatonin by upregulation of antioxidant defense system of heart, liver, and kidneys of rats. Expand
Amelioration of fluoride toxicity by vitamins and calcium on reproductive organs of female rat
TLDR
The data suggest that Fl-induced adverse effects on reproductive and other organs in female rats, whereas vitamin C, vitamin D and calcium treatment ameliorated Fl toxicity, and vitamins (C and D) and calcium play an important role in prophylactic treatment of fluorosis. Expand
Vitamins C and E attenuate lipid dystrophy in tissues of rats administered aluminium
To investigate the effects of aluminum chloride (AlCl 3 ) in the deviation of tissue lipid profiles and ways to reduce its effect using antioxidant vitamins C and E, thirty-six male albino ratsExpand
Aluminium administration is associated with enhanced hepatic oxidant stress that may be offset by dietary vitamin E in the rat
TLDR
Investigation of the effects of aluminium lactate administration on indices of hepatic oxidant stress, and the consequences of concomitant dietary vitamin E, in male albino Wistar rats found that aluminium toxicity may be mediated, at least in part, by free radical generation. Expand
The protective effect of Vitamin C and Vitamin E on some antioxidants and lipid peroxidation in blood and tissues of male albino rats treated with aluminum
Aluminum is presents in many manufactured foods, medicines and is also added to drinking water for purification purposes. Therefore, the present study included the investigation of the protectiveExpand
Induced Toxicity and Oxidative Stress in Liver of Male Rats : Protection by Melatonin
Aluminum is a ubiquitous element with known toxicity for both human and experimental animals. It has been implicated in the pathogenesis of several diseases. The present study investigates theExpand
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References

SHOWING 1-10 OF 40 REFERENCES
AMELIORATIVE ROLE OF AMINO ACIDS ON FLUORIDE- INDUCED ALTERATIONS IN UTERINE CARBOHYDRATE METABOLISM IN MICE
SUMMARY: The effects on female mice of sodium fluoride (NaF) administration, at a dose of 5 mg/kg body weight for varied durations (7, 15, 30, 45 and 60 days), were investigated in order to evaluateExpand
Effects of Combined Exposure to Aluminium and Ethanol on Aluminium Body Burden and some Neuronal, Hepatic and Haematopoietic Biochemical Variables in the Rat
TLDR
The consumption of alcohol may increase the rat's susceptability to certain effects of aluminium, as the concentration of aluminium in the blood and liver was significantly higher in rats exposed to both aluminium and ethanol than in those exposed to aluminium alone. Expand
Concurrent ingestion of lactate and aluminum can result in developmental toxicity in mice.
TLDR
The present data, as well as the results of previous studies strongly suggest that the consumption of high doses of aluminum-containing compounds should be avoided during pregnancy. Expand
Lack of maternal and developmental toxicity in mice given high doses of aluminium hydroxide and ascorbic acid during gestation.
TLDR
Although in this study aluminium hydroxide was given at doses higher than those usually consumed by pregnant women, no signs of maternal or developmental toxicity were observed when the compound was given alone or concurrently with high doses of ascorbic acid. Expand
Chronic administration of aluminum–fluoride or sodium–fluoride to rats in drinking water: alterations in neuronal and cerebrovascular integrity
This study describes alterations in the nervous system resulting from chronic administration of the fluoroaluminum complex (AlF3) or equivalent levels of fluoride (F) in the form of sodium-fluorideExpand
Accumulation of aluminium in rat liver: association with constituents of the cytosol.
TLDR
R rats were loaded with Al prior to liver fractionation by ultracentrifugation, and equilibrium gel filtration chromatography of the cytosol indicated that Al was associated with a low molecular weight form which was not a citrate complex, and a high molecular weight forms which was larger than transferrin. Expand
Inhibition of cholinesterases by fluoride in vitro.
  • G. Cimasoni
  • Chemistry, Medicine
  • The Biochemical journal
  • 1966
1. Series of colorimetric dynamic assays allowed the study of the inhibition of cholinesterases by F(-) ions in vitro, by using, as sources of enzyme, whole human blood, human serum, homogenized ratExpand
Effects of aluminium salts on synaptosomal enzymes--an in vitro kinetic study.
  • K. S. Rao
  • Medicine
  • Biochemistry international
  • 1990
TLDR
Kinetics of Ca2(+)-ATPase inhibition by AlF3 was found to be non-competitive and the Toxicity Test Value, Maximum Chemical Acceptability Value and Omega value indicated salt specific toxicity. Expand
Protein measurement with the Folin phenol reagent.
TLDR
Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein. Expand
COMPARISON OF RED AND WHITE VOLUNTARY SKELETAL MUSCLES OF SEVERAL SPECIES OF PRIMATES
TLDR
The soleus, sartorius and brachioradialis from 10 other species of primates had the same relative succinic dehydrogenase activities and histochemical staining patterns as the rhesus. Expand
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3
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