BEACH-domain proteins act together in a cascade to mediate vacuolar protein trafficking and disease resistance in Arabidopsis.

@article{Teh2015BEACHdomainPA,
  title={BEACH-domain proteins act together in a cascade to mediate vacuolar protein trafficking and disease resistance in Arabidopsis.},
  author={Ooi-kock Teh and Noriyuki Hatsugai and Kentaro Tamura and Kentaro Fuji and Ryo Tabata and Katsushi Yamaguchi and Shuji Shingenobu and Masashi Yamada and Mitsuyasu Hasebe and Shinichiro Sawa and Tomoo Shimada and Ikuko Hara-Nishimura},
  journal={Molecular plant},
  year={2015},
  volume={8 3},
  pages={
          389-98
        }
}
Membrane trafficking to the protein storage vacuole (PSV) is a specialized process in seed plants. However, this trafficking mechanism to PSV is poorly understood. Here, we show that three types of Beige and Chediak-Higashi (BEACH)-domain proteins contribute to both vacuolar protein transport and effector-triggered immunity (ETI). We screened a green fluorescent seed (GFS) library of Arabidopsis mutants with defects in vesicle trafficking and isolated two allelic mutants gfs3 and gfs12 with a… CONTINUE READING
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