BDNF-promoted increases in proximal dendrites occur via CREB-dependent transcriptional regulation of cypin.

@article{Kwon2011BDNFpromotedII,
  title={BDNF-promoted increases in proximal dendrites occur via CREB-dependent transcriptional regulation of cypin.},
  author={Munjin Kwon and Jose Roberto Fernandez and Gregory F Zegarek and Sean B. Lo and Bonnie L Firestein},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 26},
  pages={9735-45}
}
Alterations in dendrite branching and morphology are present in many neurodegenerative diseases. These variations disrupt postsynaptic transmission and affect neuronal communication. Thus, it is important to understand the molecular mechanisms that regulate dendritogenesis and how they go awry during disease states. Previously, our laboratory showed that cypin, a mammalian guanine deaminase, increases dendrite number when overexpressed and decreases dendrite number when knocked down in cultured… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 91 references

Similar Papers

Loading similar papers…