BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog.

@article{Fahnestock2012BDNFIW,
  title={BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog.},
  author={Margaret Fahnestock and Monica Marchese and Elizabeth Head and Viorela Pop and Bernadeta Michalski and William N Milgram and Carl Cotman},
  journal={Neurobiology of aging},
  year={2012},
  volume={33 3},
  pages={546-54}
}
The aged canine (dog) is an excellent model for investigating the neurobiological changes that underlie cognitive impairment and neurodegeneration in humans, as canines and humans undergo similar pathological and behavioral changes with aging. Recent evidence indicates that a combination of environmental enrichment and antioxidant-fortified diet can be used to reduce the rate of age-dependent neuropathology and cognitive decline in aged dogs, although the mechanisms underlying these changes… CONTINUE READING

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