BDNF Val66Met polymorphism is associated with abnormal interhemispheric transfer of a newly acquired motor skill.

@article{MorinMoncet2014BDNFVP,
  title={BDNF Val66Met polymorphism is associated with abnormal interhemispheric transfer of a newly acquired motor skill.},
  author={Olivier Morin-Moncet and Vincent Beaumont and Louis de Beaumont and Jean-François Lepage and Hugo Th{\'e}oret},
  journal={Journal of neurophysiology},
  year={2014},
  volume={111 10},
  pages={2094-102}
}
Recent data suggest that the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene can alter cortical plasticity within the motor cortex of carriers, which exhibits abnormally low rates of cortical reorganization after repetitive motor tasks. To verify whether long-term retention of a motor skill is also modulated by the presence of the polymorphism, 20 participants (10 Val66Val, 10 Val66Met) were tested twice at a 1-wk interval. During each visit, excitability of the motor… CONTINUE READING