BDNF-TrkB signaling interacts with the GABAergic system to inhibit rhythmic swallowing in the rat.


Brain-derived neurotrophic factor (BDNF) acts as an anorexigenic factor in the dorsal vagal complex (DVC) of the adult rat brain stem. The DVC contains the premotoneurons controlling swallowing, a motor component of feeding behavior. Although rats with transected midbrain do not seek out food, they are able to swallow and to ingest food. Because BDNF and… (More)
DOI: 10.1152/ajpregu.90407.2008


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