BDNF/trkB signaling in the developmental sculpting of visual connections.

Abstract

Neurotrophins are a family of secreted molecules that have multiple, profound actions on the structure and function of both developing and mature neurons. Neurotrophins exert their influences by signaling through the trk family of receptor tyrosine kinases and the p75 low affinity neurotrophin receptor. Here we review the contributions of neurotrophins to… (More)

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