BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.

@article{Mohankumar2015BDMCAAA,
  title={BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.},
  author={Kumaravel Mohankumar and Subhashree Sridharan and Sankar Pajaniradje and Vivek Kumar Singh and Larance Ronsard and Akhil Chandra Banerjea and Dinesh Babu Somasundaram and Mohane Selvaraj Coumar and Latha Periyasamy and Rukkumani Rajagopalan},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2015},
  volume={74},
  pages={
          178-86
        }
}
Breast cancer chemoprevention has become increasingly important in India as it faces a potential breast cancer epidemic over the next decade. Curcumin, the active ingredient in turmeric is a well known chemopreventive agent that possesses various therapeutic properties including antioxidants and anti-inflammatory effects. In the present study, we have investigated the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7… CONTINUE READING
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